Using Premixed Biphasic Insulin Analogs Humalog® Mix 25 and Humalog® Mix50 in Basal Bolus Format: Evidence from Research, Clinical Practice and Case Reports

Submit Manuscript | http://medcraveonline.com degludec/Tresiba®) have been proven more safer and efficacious in management of type-1 and type-2 diabetes, as compared to older or traditional insulins (Human Regular and NPH), with better glycemic control (HbA1c reductions) and less or negligible hypoglycemia; these insulin analogs are available as insulin pens and more easy to use. Furthermore, these newer insulin analogs have been proven safer for Ramadan fasting as well. Similarly, premixed or biphasic insulin analog preparations (Humalog® Mix 25, Humalog® Mix 50 and Novomix® 30) are proven for their safety, efficacy and easy usage, as compared to premixed human insulin (Human Insulin 30/70). Basal bolus format remains the best way of managing diabetes, especially type-1. This technique is somewhat difficult for type-2 older patients, however [1-8].